Living Donor Liver Transplantation for an Infant with Osteogenesis Imperfecta and Intrahepatic Cholestasis: Report of a Case
نویسندگان
چکیده
Osteogenesis imperfecta (OI) is a group of genetic disorders characterized by bone fragility and connective tissue manifestations. We report a successful liver transplantation (LT) in an 8-month-old boy with OI and cholestatic biliary cirrhosis. After 4 cycles of intravenous pamidronate, LT was performed under intravenous anesthesia using a left lateral section from his mother without mechanical retractors. The operation time was 420 min and estimated blood loss was 520 mL requiring one unit of RBC transfusion. He was discharged without surgical complications. Therefore, LT should be considered for patients with end stage liver disease and OI under organic multidisciplinary cooperation.
منابع مشابه
Liver transplantation in a child with osteogenesis imperfecta
read with great interest the case report by Lee et al. [1], of the anesthetic management of an infant with osteogenesis im-perfecta (OI) and progressive familial intrahepatic cholestasis, who was undergoing orthotopic liver transplantation (OLT). This case was indeed challenging, but we would like to add the following comments. First, OI is only weakly associated with malignant hyperther-mia, i...
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